September 27, 2006

Diseases Treated by Stem Cells - New Stem Cell Application

Emerging Stem Cell Applications*
Alzheimer's Disease
Diabetes
Heart Disease
Liver Disease
Muscular Dystrophy
Parkinson's Disease
Spinal Cord Injury
Stroke

* Chen, Jieli, et al. Expression of neural markers in human umbilical cord blood. Experimental Neurology.2001;171:109-115
  Pessina, A., et al. Pancreas developing markers expressed on human mononucleated umbilical cord blood cells. Biochemical and Biophysical Research Communications.2004;323:315-322
  Botta, Rosanna, et al. Heart infarct in NOD-SCID mice: Therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+cells. The FASEB Journal.2004;18:1392-1394
  Perin, E., et al. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation.2003;107:2294-2302
  Campli, C., et al. A human umbilical cord stem cell rescue therapy in a murine model of toxic liver injury. Digestive and Liver Disease.2004;36:603-613
  Gussoni, E., et al. Long term persistence of donor nuclei in a duchenne muscular dystrophy patient receiving bone marrow transplantation. The Journal of Clinical Investigation.2002;110(6):807-814
  Saporta, Samuel, et al. Human umbilical cord blood stem cells infusion in spinal cord injury: Engraftment and beneficial influence on behavior. Journal of Hematotherapy & Stem Cell Research.2003;12:271-278
  Vendrame, Martina, et al. Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume. Stroke.2004;35:2390-2395.

02:23 PM in Diseases Treated | | Comments (0) | TrackBack (0)

September 26, 2006

Diseases Treated by Stem Cells - Other Malignancies

Current Stem Cell Applications For Other Malignancies
Brain Tumors
Ewing Sarcoma
Neuroblastoma
Ovarian Cancer
Renal Cell Carcinoma
Small-Cell Lung Cancer
Testicular Cancer

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September 25, 2006

Diseases Treated by Stem Cells - Abnormalities

Current Stem Cell Applications For Abnormalities

Inherited Erythrocyte Abnormalities
Beta Thalassemia Major
Blackfan-Diamond Anemia
Pure Red Cell Aplasia
Sickle Cell Disease

Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia

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September 24, 2006

Diseases Treated by Stem Cells - Syndromes

Current Stem Cell Applications For Syndromes
Myelodysplastic Syndromes
Amyloidosis
Chronic Myelomonocytic Leukemia (CMML)
Refractory Anemia (RA)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation
   (RAEB-T)
Refractory Anemia with Ringed Sideroblasts (RARS)

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September 23, 2006

Diseases Treated by Stem Cells - Diseases

Current Stem Cell Applications For Diseases
Liposomal Storage Diseases
Adrenoleukodystrophy
Alpha Mannosidosis
Gaucher's Disease
Hunter's Syndrome (MPS-II)
Hurler's Syndrome (MPS-IH)
Krabbe Disease
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Morquio Syndrome (MPS-IV)
Mucolipidosis II (I-cell Disease)
Mucopolysaccharidoses (MPS)
Niemann-Pick Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
Wolman Disease


Autoimmune Diseases
Multiple Sclerosis (experimental)
Rheumatoid Arthritis (experimental)
Systemic Lupus Erythematosus (experimental)

09:30 AM in Diseases Treated | | Comments (0) | TrackBack (0)

September 22, 2006

Diseases Treated by Stem Cells - Disorders

Although not all diseases treated with stem cells have been treated specifically with cord blood stem cells, doctors have been using cord blood in lifesaving treatments since 1988. And recently, scientists have discovered some amazing new possibilities for treating diseases and injuries in the future.

Current Stem Cell Applications For Disorders

Stem Cell Disorders
Aplastic Anemia (Severe)
Congenital Cytopenia
Dyskeratosis Congenita
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)

Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Essential Thrombocythemia
Polycythemia Vera

Lymphoproliferative Disorders
Hodgkin's Disease
Non-Hodgkin's Lymphoma
Prolymphocytic Leukemia

Phagocyte Disorders
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis

Histiocytic Disorders
Familial Erythrophagocytic Lymphohistiocytosis
Hemophagocytosis
Histiocytosis-X
Langerhans' Cell Histiocytosis

Congenital (Inherited) Immune System Disorders
Absence of T and B Cells SCID
Absence of T Cells, Normal B Cell SCID
Ataxia-Telangiectasia
Bare Lymphocyte Syndrome
Common Variable Immunodeficiency
DiGeorge Syndrome
Kostmann Syndrome
Leukocyte Adhesion Deficiency
Omenn's Syndrome
Severe Combined Immunodeficiency (SCID)
SCID with Adenosine Deaminase Deficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

Other Inherited Disorders
Cartilage-Hair Hypoplasia
Ceroid Lipofuscinosis
Congenital Erythropoietic Porphyria
Glanzmann Thrombasthenia
Lesch-Nyhan Syndrome
Osteopetrosis
Sandhoff Disease

Plasma Cell Disorders
Multiple Myeloma
Plasma Cell Leukemia
Waldenstrom's Macroglobulinemia

12:22 PM in Diseases Treated | | Comments (0) | TrackBack (0)

Diseases Treated by Stem Cells - Leukemias

Although not all diseases treated with stem cells have been treated specifically with cord blood stem cells, doctors have been using cord blood in lifesaving treatments since 1988. And recently, scientists have discovered some amazing new possibilities for treating diseases and injuries in the future.

Current Stem Cell Applications For Leukemia

Acute Leukemias
Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia

Chronic Leukemias
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)

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